Rare diseases and cancer
with unmet medical needs

SHIFTBIO’s pipeline is aiming to cure orphan diseases and cancer. 

Candidate

SBI-101
[SIRP-Exo]

Indication

Immunotherapy resistant
solid tumor

2022
2023
2024~
Discovery
Pre-Clinical
IND
Clinical

Candidate

SBI-102

[SIRP-Exo, MSC]

Indication

NASH with liver Fibrosis
Acute Liver Failure

2022
2023
2024~
Discovery
Pre-Clinical
IND
Clinical

Candidate

SBI-103
[EGF-Exo] 

Indication

Undisclosed 

2022
2023
2024~
Discovery
Pre-Clinical

Candidate

SBI-104
[Apelin-Exo] 

Indication

Pulmona
arterial hypertension

2022
2023
2024~
Discovery
Pre-Clinical
IND

Candidate

SBI-205
[Exo-HIF1α] 

Indication

Liver damage 

2022
2023
2024~
Discovery
Pre-Clinical
IND

Candidate

SBI-306
[RSFV-Exo-UP] 

Indication

Immunotherapy
resistant solid tumor

2022
2023
2024~
Discovery

Candidate

SBI-407 
[Fc-Exo, MSC] 

Indication

Undisclosed 

2022
2023
2024~
Discovery

Candidate

SBI-508
[Ag-Exo]

Indication

Immunotherapy
resistant solid tumor

2022
2023
2024~
Discovery

Candidate

SBI-609, LGP-S01
[ImmuNano]

Indication

Undisclosed

2022
2023
2024~
Pre-Clinical
IND
Clinical

Rare diseases and cancer
with unmet medical needs

SHIFTBIO’s pipeline is aiming to cure orphan diseases and cancer. 

Candidate

Indication

2022
2023
2024~

SBI-101

[SIRP-Exo]

Immunotherapy resistant
solid tumor


Discovery


Pre-Clinical
IND
Clinical

SBI-102

[SIRP-Exo, MSC]

NASH with liver fibrosis
Acute Liver Failure

SBI-103

[EGF-Exo]

Undisclosed

Discovery
Pre-Clinical

SBI-104

[Apelin-Exo]

Pulmonary
arterial hypertension

Discovery


Pre-Clinical
IND

SBI-205

[Exo-HIF1α]

Liver damage

SBI-306

[RSFV-Exo-UP]

Immunotherapy resistant
solid tumor

Discovery

SBI-407

[Fc-Exo, MSC]

Undisclosed
Discovery
SBI-508

[Ag-Exo]

Immunotherapy resistant
solid tumor

Discovery

SBI-609, LGP-S01

[ImmuNano]

Undisclosed
Pre-Clinical
IND
Clinical