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First Program

Inflammatory dying cells exacerbate inflammatory diseases
by markedly elevating CD47 expression, thereby strategically evading their removal. 

CD47, ‘Don’t eat me signal’





Uncleared Inflammatory Dying Cells:
Worsening Diseases

SIRP-NV (SBI-102), Immunotherapy to remove the pathological cells 

SBI-102 pioneers the concept of immunotherapy, Awakening the body’s innate immune system to amplify its regenerative potential

SBI-102 can be the game changer
of the CD47 blockade.

CD47 degradation

High safety

Enhanced efficacy through clustering

SIRP-NV demonstrates high expandability in indication, starting from a nichebuster for rare diseases and evolving into a blockbuster for intractable diseases.