Engineered stem cell-derived SIRP-NNP pioneers the concept of regenerative
immunotherapy, reprogramming
macrophages toward inflammation-
resolving and regenerative phenotypes
SIRP-NNP-MSC
Targeted Delivery
to Inflamed Tissue
Targeting CD47, overexpressed on inflamed tissues, enables targeted delivery and macrophage-mediated clearance
Delivering MSC cargo
Delivering MSC-derived SIRP-NNP’s
regenerative cargo to macrophages
CD47 Overexpression |
 |
In vivo Macrophage |
 |
Recovery |
 |
Engineered stem cell-derived SIRP-NNP pioneers the concept of regenerative immunotherapy,
reprogramming macrophages toward inflammation-resolving and regenerative phenotypes
SIRP-NNP-MSC
Targeted Delivery
to Inflamed Tissue
Targeting CD47, overexpressed on inflamed tissues, enables targeted delivery and macrophage-mediated clearance
Delivering
MSC cargo
Delivering MSC-derived
SIRP-NNP’s regenerative cargo
to macrophages
CD47 Overexpression | In vivo Macrophage Reprogramming | Recovery |
| |
|
