Inflammatory dying cells exacerbate inflammatory diseases
by markedly elevating CD47 expression, thereby strategically evading their removal. 

CD47, ‘Don’t eat me signal’





Uncleared Inflammatory Dying Cells:
Worsening Diseases


Regenerative Immunotherapy,
Engineered stem cell-derived

SIRP-NV (SBI-102) 

SBI-102 pioneers the concept of regenerative immunotherapy, awakening the body's innate immune system to amplify its regenerative potential. 


Regenerative Immunotherapy,
Engineered stem cell-derived SIRP-NV (SBI-102) 

SBI-102 pioneers the concept of regenerative immunotherapy,
awakening the body's innate immune system to amplify its regenerative potential. 

CD47 degradation by SIRP-NV

Paracrine effects of stem cells


SBI-102 can be the game changer
of the CD47 blockade.

CD47 degradation

High safety

Stem cell effect


SBI-102, exhibits high target disease expandability, starting with nichebuster therapies for rare diseases and expanding towards blockbuster treatments for intractable diseases. .

Expanding SIRP-NV's versatility for a wide range of applications.