Rare diseases and cancer
with unmet medical needs

SHIFTBIO’s pipeline is aiming to cure orphan diseases and cancer. 

Candidate

SBI-101 [SIRP-Exo]

Indication

Immunotherapy resistant solid tumor

Rights

Discovery

Pre-clinical


Candidate

SBI-101 [SIRP-Exo]

Indication

Immunotherapy resistant solid tumor

Rights

Discovery

Pre-clinical


Candidate

SBI-101 [SIRP-Exo]

Indication

Immunotherapy resistant solid tumor

Rights

Discovery

Pre-clinical


Candidate

SBI-101 [SIRP-Exo]

Indication

Immunotherapy resistant solid tumor

Rights

Discovery

Pre-clinical


Rare diseases and cancer with unmet medical needs

SHIFTBIO’s pipeline is aiming to cure orphan diseases and cancer. 

Candidate

Indication

Development Phases

Rights

Discovery

Pre-clinical

SBI-101

[SIRP-Exo]

Immunotherapy resistant
solid tumor


SBI-102

[SIRP-Exo, MSC]

NASH with liver fibrosis
Acute Liver Failure


SBI-103

[EGF-Exo]

Undisclosed


SBI-104

[Apelin-Exo]

Pulmonary
arterial hypertension

SBI-205

[Exo-HIF1α]

Liver damage


SBI-306

[RSFV-Exo-UP]

Immunotherapy resistant
solid tumor


SBI-407

[Fc-Exo, MSC]

Undisclosed

SBI-508

[Ag-Exo]

Immunotherapy resistant
solid tumor




SBI-609, LGP-S01

[ImmuNano]

Undisclosed